From New York Times bestselling author and neuroscientist Lisa Genova comes a "heartbreaking…very human novel" (Matthew Thomas, author of We Are Not Ourselves) that does for Huntington's disease what her debut novel Still Alice did for Alzheimer's.
Joe O'Brien is a forty-three-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his family's lives forever: Huntington's disease.
Huntington's is a lethal neurodegenerative disease with no treatment and no cure, and each of Joe's four children has a 50 percent chance of inheriting their father's disease. While watching her potential future in her father's escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. As Joe's symptoms worsen and he's eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life "at risk" or learn their fate.
Praised for writing that "explores the resilience of the human spirit" (San Francisco Chronicle), Lisa Genova has once again delivered a novel as powerful and unforgettable as the human insights at its core.
"A gut-wrenching and memorable read." ―Library Journal (starred review)
"Genova's book will move readers as well as demystify a condition sometimes called 'the cruelest disease known to man." ― Publishers Weekly
"Sympathetic, absorbing, multifaceted characters compel the reader's compassion. While Genova's background in neuroscience allows her to portray medical issues accurately, the heart of the O'Briens' story is human....Poignant and painful, warm and redemptive, Inside the O'Briens displays Genova's established strengths in bringing neuroscience to the lay reader, and portraying the power of love." ―Shelf Awareness
"Lisa Genova's deep empathy for her characters shines through this poignant and uplifting story about family, grief and the resilience of the human spirit. Kudos to this amazing writer for showing us—once again—the transformative powers of even the most devastating events. Do not miss this fabulous novel." ―Barbara Shapiro, author of The Muralist and The Art Forger
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Any "Author Information" displayed below reflects the author's biography at the time this particular book was published.
Lisa Genova graduated valedictorian, summa cum laude from Bates College with a degree in Biopsychology and has a Ph.D. in Neuroscience from Harvard University. Acclaimed as the Oliver Sacks of fiction and the Michael Crichton of brain science, she is the author of the New York Times bestselling novels Still Alice, Left Neglected, Love Anthony, and Inside the O'Briens.
Still Alice spent 59 weeks on the New York Times bestseller list. It won the 2008 Bronte Prize and the 2011 Bexley Book of the Year, and it was nominated for the 2010 Indies Choice Debut Book of the Year by the American Booksellers Association. It was the #6 Top Book Group Favorite of 2009 by Reading Group Choices, a 2009 Barnes & Noble Discover Pick, a 2009 Indie Next pick, a 2009 Borders Book Club Pick, and a 2009 ...
... Full Biography
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Link to Lisa Genova's Website
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