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Serendipity in Modern Medical Breakthroughs
by Morton Meyers M.D.The heroes of the stories told in this book are not scientists who
merely plodded rationally from point A to point B, but rather those
who came upon X in the course of looking for Y, and saw its potential
usefulness, in some cases to a field other than their own. Chance is but
one element, perhaps the catalyst for creativity in scientific research.
And, yes, the process of discovery is indeed creative. It involves unconscious
factors, intuition, the ability to recognize an important
anomaly or to draw analogies that are not obvious. A creative mind is
open and can go beyond linear reasoning to think outside the box,
look beyond conventional wisdom, and seize on the unexpected. Most
important, a creative scientific mind recognizes when it is time to start
viewing something from a whole new perspective.
Turning Reality on Its Side
One day in 1910, the Russian painter Wassily Kandinsky returned to
his studio at dusk and was confronted with an object of dazzling
beauty on his easel. In the half-light, he could make out no subject but
was profoundly moved by the shapes and colors in the picture. It was
only then that he realized the painting was resting on its side. Like an
epiphany, this experience confirmed his growing belief in the emotional
powers of colors and in the ultimate redundancy of the traditional
subject of a picture. Kandinsky, who broke through to what he
called nonobjective painting, is widely acknowledged as the father
of abstract art.
By dipping into the world of art, and especially into visual illusions,
scientists can gain perspective on illusions of judgment, also
known as cognitive illusions. Gestalt psychologists have elaborated on
such things as the balances in visual perception between foreground
and background, dark and light areas, and convex and concave contours.
The gist of their message is that too-close attention to detail
may obscure the view of the whole a message with special meaning
for those alert to serendipitous discovery.
To readily appreciate this phenomenon, consider the paintings of
the contemporary artist Chuck Close. Viewed at the usual distance,
they are seen as discrete squares of lozenges, blips, and teardrops.
Detail from Chuck Close's Kiki - left eye.
Viewed from a much greater distance, they can be appreciated as
large, lifelike portraits.
Chuck Close, Kiki, 1973. Oil on canvas, 100 x 84 in. Walker Art Center, Minneapolis.
In a Gestalt figure, such as the M. C. Escher drawing on the next
page, one can see the devils or the angels, but not both at the same
time. Even after you know that there is more than one inherent pattern,
you see only one at a time; your perception excludes the others.
M. C. Escher, Circle Limit IV, 1960. Woodcut in black and ochre, printed from
two
blocks.
The same holds true for W. E. Hills My Wife and My Mother-in- Law. Its easy to see his dainty wife, but you have to alter your whole way of making sense of the lines to see the big-nosed, pointy-chinned mother-in-law.
W. E. Hill, My Wife and My
Mother-in-Law, 1915.
Certainly, if ones perspective is too tightly focused, gross distortion
may result. This phenomenon has broad implications for medical
research. So does the human tendency to believe that ones partial
view of an image or, indeed, a view of the world captures its entirety.
We often misjudge or misperceive what is logically implied or
actually present. In drama this may lead to farce, but in science it leads
to dead ends.
Excerpted from Happy Accidents by Morton Meyers, M.D. Copyright © 2007 by Morton Meyers, M.D. Excerpted by permission of Arcade Publishing. All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
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