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In the shadow of New York City lies an unimposing 840-acre island unidentified on most maps. Lab 257 takes you deep inside Plum Island's laboratories and presents startling revelations including virus outbreaks, biological meltdowns and the connections between Plum Island, Lyme disease and the West Nile virus.

An epic history of the deadliest plague in human history - the great flu epidemic of 1918, which killed seven times as many people as died in the First World War.